Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. The Toyota is significantly cheaper to get to the dealership than the GMC.
The Toyota Sienna isn't much less expensive than the GMC when it comes to MSRP.
Utility
Drivers with frequent kid-duty might favor the GMC Savana 2500 over the Toyota Sienna.
The GMC Savana 2500 is likely a better choice than the Toyota Sienna with respect to transporting cargo, especially if you frequently need to carry a lot of equipment or big dogs.
Towing is considerably more the GMC Savana 2500's forte than it is the Sienna's.
Comfort
Taller drivers will considerably enjoy the extra head room in the Toyota Sienna's front cabin compared to the GMC.
The Sienna offers more head- and leg-room to your passengers than the GMC Savana 2500 does.
Dimensions
The GMC is substantially more bulky than the Sienna.
Your wallet will hurt more every time you fill up the GMC Savana 2500 than the Toyota because of its bigger tank.
The Sienna and the Savana 2500 compete for the same parking spaces.
The Toyota Sienna's shorter wheelbase will give a more maneuverable feel in daily traffic. However, the GMC Savana 2500 is likely to have a smoother, more stable ride.
Handling
With its tighter turning circle, the Sienna is quite certainly more maneuverable than the GMC, something to consider if you do a lot of city driving; however, remember that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The Toyota's engine is tremendously smaller than the GMC's. Bear in mind that smaller engines can be stressed more; on the flip side, smaller engines typically get better gas mileage.
The GMC Savana 2500 packs quite a wallop compared to the Sienna in terms of torque, which is the force that lets you accelerate quickly.
The Toyota Sienna could learn a lesson or two from the GMC Savana 2500 regarding torque.
Warranty
The GMC Savana 2500 and the Toyota have the same basic after-sale protection.