Utility
The Toyota Sequoia will most certainly prove more practical than the Mercedes-Benz GL-Class for those of you with frequent kid-cargo.
The GL-Class is likely a better choice than the Toyota Sequoia as far as transporting cargo, especially if you frequently need to carry a lot of cargo or animals.
The Toyota outpulls the Mercedes-Benz GL-Class by a large margin.
Performance
With that kind of horsepower, both the Mercedes-Benz GL-Class and the Toyota Sequoia are true sportscars.
Dimensions
The Mercedes-Benz GL-Class and the Toyota compete for the same parking spaces.
Convenience
The Mercedes-Benz's fuel tank will need to be replenished a tad more often than the unit in the Sequoia.
Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. It costs approximately the same to get the Mercedes-Benz GL-Class to the dealership as the Toyota Sequoia.
With respect to fuel economy, the Toyota Sequoia is somewhat better than the GL-Class, but not by much.
The Toyota Sequoia won't save you much money at the pump compared to the Mercedes-Benz GL-Class.
In terms of MSRP, the Toyota Sequoia costs significantly less than the GL-Class.
Handling
With their comparable turning radii, the Sequoia and the GL-Class quite certainly handle approximately the same into and out of tight spots.
Drivetrain
The Toyota Sequoia and the GL-Class have similar-sized engines, with a slight advantage to the GL-Class.
Comfort
Taller drivers will significantly enjoy the extra head room in the Mercedes-Benz GL-Class's front cabin compared to the Toyota Sequoia.
The Mercedes-Benz GL-Class provides more head- and leg-room to your passengers than the Toyota Sequoia does.
Warranty
The basic warranty that comes with the Toyota Sequoia isn't quite as generous as the Mercedes-Benz GL-Class's.