Utility
Drivers with frequent child-duty might favor the Toyota Sequoia over the Acura MDX.
The Toyota Sequoia is likely a better choice than the Acura MDX as far as hauling capacity, especially if you often need to carry a lot of gear or large dogs.
Towing is considerably more the Toyota Sequoia's forte than it is the Acura MDX's.
Performance
In terms of horsepower, the Toyota Sequoia packs quite a punch and will knock the Acura MDX down a few rungs. On the other hand, remember that high horsepower engines often command higher insurance premiums.
With that kind of horsepower, both the Toyota Sequoia and the Acura MDX are true speedsters.
Dimensions
The Sequoia is considerably heavier than the Acura MDX.
Your wallet will hurt more every time you fill up the Toyota Sequoia than the Acura MDX because of its bigger tank.
The MDX and the Sequoia compete for the same parking spaces.
The Acura's shorter wheelbase will give a more maneuverable feel in daily traffic. However, the Toyota is likely to have a smoother, more stable ride.
Convenience
You will most certainly have to visit your friendly gas station more often with the Acura MDX than with the Toyota Sequoia.
Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. The Acura is considerably cheaper to get to the dealership than the Toyota Sequoia.
Producing a precise fuel economy evaluation is so difficult that some think not even the federal government can do it, but it looks as though both the Acura MDX and the Acura MDX perform roughly similarly as far as fuel economy.
The Toyota Sequoia won't tax your gasoline budget significantly more than the Acura MDX will.
The Acura MDX isn't much less pricey than the Toyota Sequoia in terms of MSRP.
Handling
With their comparable turning circles, the Acura MDX and the Toyota Sequoia likely handle almost the same into and out of tight spots.
Drivetrain
The Acura's engine is considerably smaller than the Toyota Sequoia's. Keep in mind that a smaller engine usually has to work a little harder; however, smaller engines typically get better gas mileage.
Torque equals pickup, and the Sequoia will have picked up and gone by the time the Acura MDX finally gets moving.
Torque is the force that lets you accelerate quickly, and in this respect, the Toyota Sequoia is considerably more powerful than the Acura MDX.
Comfort
While the front cabin in the MDX offers a bit more head room than the Toyota Sequoia, there really isn't much of a difference.
The ampler interior dimensions of the Acura MDX make it roomier for your passengers than the Toyota Sequoia.
Warranty
The basic warranty that comes with the Sequoia isn't quite as generous as the Acura MDX's.