Utility
The Acura MDX and the Toyota Highlander Hybrid can accommodate the same number of passengers.
The Toyota Highlander Hybrid is a better choice than the Acura MDX when it comes to hauling capacity, especially if you often need to carry a lot of gear or sizeable animals.
The Acura MDX outpulls the Toyota by a massive margin.
Performance
As far as horsepower, the Acura MDX packs quite a wallop and will knock the Toyota Highlander Hybrid down a few rungs. However, bear in mind that high horsepower engines often command higher insurance premiums.
Dimensions
Your wallet will hurt more every time you fill up the MDX than the Toyota Highlander Hybrid because of its larger tank.
The Highlander Hybrid and the MDX compete for the same parking spaces.
Convenience
The Acura's fuel tank will need to be replenished more often than the unit in the Toyota Highlander Hybrid.
Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. It costs roughly the same to get the Toyota Highlander Hybrid to the dealership as the Acura MDX.
In terms of gas mileage, the Toyota Highlander Hybrid beats the Acura.
Regarding MSRP, the MDX costs approximately as much as the Toyota Highlander Hybrid (though the Toyota Highlander Hybrid is slightly cheaper).
The Acura MDX will cost you a bundle in gasoline every year compared to the Toyota Highlander Hybrid.
The Highlander Hybrid will save you a bundle at the pump every year compared to the Acura MDX.
Handling
With their similar turning radii, the MDX and the Toyota Highlander Hybrid quite certainly handle approximately the same into and out of tight spots.
Drivetrain
The Toyota Highlander Hybrid and the Acura MDX have similar-sized engines, with a slight advantage to the Acura MDX.
The Toyota Highlander Hybrid could learn a lesson or two from the MDX as far as torque.
Torque is roughly equivalent to acceleration, and in this respect, the Acura MDX is significantly more powerful than the Toyota Highlander Hybrid.
Comfort
Taller drivers will considerably enjoy the extra head room in the Toyota Highlander Hybrid's front cabin compared to the Acura MDX.
The Toyota Highlander Hybrid is not particularly more spacious for your passengers than the Acura.
Warranty
The basic after-sale protection that comes with the Toyota Highlander Hybrid isn't quite as generous as the MDX's.