Cost
The 4Runner won't tax your gasoline budget significantly more than the Toyota Highlander will.
The Highlander will save you money at the pump compared to the 4Runner.
The Highlander isn't much less costly than the 4Runner regarding MSRP.
Utility
Drivers with frequent kid-duty might favor the Highlander over the 4Runner.
The Toyota Highlander is a better choice than the Toyota 4Runner as far as hauling capacity, especially if you frequently need to carry a lot of gear or massive dogs.
The Toyota 4Runner outpulls the Toyota Highlander by a sizeable margin.
Convenience
You'll definitely take the Highlander for a fill-up roughly as often as the Toyota 4Runner.
Comfort
While the front cabin in the Highlander offers a bit more head room than the Toyota 4Runner, there really isn't much of a difference.
The ampler interior dimensions of the Highlander make it considerably roomier for your passengers than the Toyota 4Runner.
Dimensions
The Toyota 4Runner is considerably more bulky than the Toyota Highlander.
Your wallet will hurt more every time you fill up the 4Runner than the Highlander because of its larger tank.
The Toyota Highlander and the Toyota 4Runner compete for the same parking spaces.
Handling
With their similar turning radiuses, the 4Runner and the Toyota Highlander most certainly handle approximately the same into and out of tight spots.
Drivetrain
The Toyota 4Runner's engine is considerably larger than the Toyota Highlander's. Note that more sizeable engines may use more gasoline than smaller ones.
Torque is roughly equivalent to acceleration, and in this respect, the Toyota 4Runner isn't much more powerful than the Toyota Highlander.
Overview
The Toyota Highlander and the Toyota 4Runner have the same basic warranty.