Cost
Producing a precise gas mileage evaluation is so difficult that some think not even the federal government can do it, but it looks as though the Highlander is the winner when it comes to fuel economy.
The Nissan Xterra will tax your gasoline budget substantially more than the Highlander will.
The Nissan Xterra isn't much less expensive than the Toyota Highlander when it comes to MSRP.
Utility
The Toyota Highlander will most certainly prove friendlier than the Nissan Xterra for those of you with frequent child-cargo.
The Toyota is likely a better choice than the Nissan Xterra regarding transporting cargo, especially if you often need to carry a lot of loot or big pets.
The Nissan Xterra outpulls the Toyota Highlander by a sizeable margin.
Convenience
You'll most definitely take the Nissan Xterra for a fill-up almost as often as the Toyota Highlander.
Comfort
While the front cabin in the Toyota Highlander offers a bit more head room than the Nissan Xterra, there frankly isn't much of a difference.
The ampler interior dimensions of the Toyota Highlander make it substantially more spacious for your passengers than the Nissan Xterra.
Dimensions
The Toyota Highlander's tank is almost the same size as the Nissan's, though the Nissan Xterra's is a tad larger.
The Nissan and the Toyota Highlander compete for the same parking spaces.
Handling
With their comparable turning circles, the Nissan and the Toyota Highlander most definitely handle roughly the same into and out of tight spots.
Drivetrain
The Nissan Xterra has a more sizeable engine than the Toyota Highlander. Bear in mind that smaller engines are often cheaper to fix, but smaller engines can be stressed more.
Torque is roughly equivalent to acceleration, and in this respect, the Nissan Xterra is considerably more powerful than the Toyota Highlander.
Warranty
The Highlander and the Nissan have the same basic warranty.