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Comfort
Due to its greater rear head- and legroom, backseat passengers will be able to stretch out a lot more in the Lexus GS 350 than the Lexus IS 350.
The Lexus IS 350 will be a favorite with taller drivers due to its greater front head- and legroom than the Lexus GS 350.
Convenience
You'll be making about the same number of stops at the gas station with the Lexus GS 350 as you will with the Lexus IS 350, as they get the same number of miles per tank of gas.
Cost
There are a lot of factors to consider when calculating the overall cost of a vehicle. The main consideration is Manufacturer's Suggested Retail Price (MSRP). The Lexus GS 350 will definitely make more of a dent in your wallet than the Lexus IS 350, which has a much lower MSRP.
Another consideration is the Destination Charge, which is a standard charge for transporting the vehicle to the dealer from where it's built. The Lexus GS 350 and the Lexus IS 350 have similar Destination Charges.
Dimensions
The Lexus GS 350 is a little wider than the Lexus IS 350, so getting in and out of the car in a crowded parking lot may be a little more of a squeeze.
For some people, bigger is better. If that's the case for you, then you'll be happier with the Lexus GS 350, which is slightly longer than the Lexus IS 350.
Drivetrain
With similar torque, the Lexus GS 350 and the Lexus IS 350 do an equal job of transmitting their engine's power to their wheels.
Handling
The Lexus GS 350 has about the same turning radius as the Lexus IS 350, allowing equal maneuverability in and out of tight spots.
Performance
In terms of horsepower, it's basically a tie between the Lexus GS 350 and the Lexus IS 350.
Utility
In terms of seating you'll be able to fit the same number of people in both the Lexus GS 350 and the Lexus IS 350.
With its significantly greater cargo capacity, the Lexus GS 350 will be able to haul more equipment or luggage than the Lexus IS 350.
Warranty
The Lexus GS 350 comes with essentially the same basic warranty as the Lexus IS 350.
Compare the 2017 Lexus GS 350 and the 2017 Lexus IS 350. 
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2017 Lexus
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2017 Lexus
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| Cash Back Rebate: | Visit Rebate Center | Visit Rebate Center |
| Low APR Loan: | -- | -- |
| Lease Incentive: | -- | -- |
| City MPG: | 19 - 20 | 19 |
| Highway MPG: | 26 - 28 | 26 - 28 |
| Engine(s): | V-6 | V-6 |
| Seating Capacity: | 5 | 5 |
| Basic Warranty: | 4 years/50,000 miles | 4 years/50,000 miles |
Overall Safety Rating 
Vehicle crash and safety data is provided by NHTSA, the National Highway Traffic Safety Administration. The NHTSA testing was established by Congress to reduce highway deaths and injuries. Read an article on the current NHTSA crash test program. |
Not Tested |  |
| Frontal Crash Rating
Vehicle crash and safety data is provided by NHTSA, the National Highway Traffic Safety Administration. The NHTSA testing was established by Congress to reduce highway deaths and injuries. Read an article on the current NHTSA crash test program. |
Not Tested | |
| Side Crash Rating
Vehicle crash and safety data is provided by NHTSA, the National Highway Traffic Safety Administration. The NHTSA testing was established by Congress to reduce highway deaths and injuries. Read an article on the current NHTSA crash test program. |
Not Tested | |
| Invoice*: | $46,839 - $52,534 | $38,474 - $40,488 |
Days on Lot measures the average number of days a model sits on a dealer's lot before it's sold. This is one predictor of a dealer's willingness to negotiate.
Monthly Trend for:
2017 Lexus GS 350
No Data
Monthly Trend for:
2017 Lexus IS 350
No Data
*MSRP and Invoice prices displayed are for educational purposes only, do not reflect the actual selling price of a particular vehicle, and do not include applicable gas taxes or destination charges.
Certain specifications, prices and equipment data have been provided under license from Chrome Data Solutions ("Chrome Data").© 2017 Chrome Data Solutions, LP. All Rights Reserved. This information is supplied for personal use only and may not be used for any commercial purpose whatsoever without the express written consent of Chrome Data. Chrome Data makes no guarantee or warranty, either expressed or implied, including without limitation any warranty of merchantability or fitness for a particular purpose, with respect to the data presented here. All specifications, prices and equipment are subject to change without notice.
