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Comfort
Due to its greater rear head- and legroom, backseat passengers will be able to stretch out a lot more in the Lexus GS 350 than the Lexus IS 350.
The Lexus IS 350 will be a favorite with taller drivers due to its greater front head- and legroom than the Lexus GS 350.
Convenience
You'll be making about the same number of stops at the gas station with the Lexus GS 350 as you will with the Lexus IS 350, as they get the same number of miles per tank of gas.
Cost
There are a lot of factors to consider when calculating the overall cost of a vehicle. The main consideration is Manufacturer's Suggested Retail Price (MSRP). The Lexus GS 350 is somewhat more expensive than the Lexus IS 350.
Another consideration is the Destination Charge, which is a standard charge for transporting the vehicle to the dealer from where it's built. The Lexus GS 350 and the Lexus IS 350 have similar Destination Charges.
Dimensions
The Lexus GS 350 is a little wider than the Lexus IS 350, so getting in and out of the car in a crowded parking lot may be a little more of a squeeze.
For some people, bigger is better. If that's the case for you, then you'll be happier with the Lexus GS 350, which is slightly longer than the Lexus IS 350.
Drivetrain
With similar torque, the Lexus GS 350 and the Lexus IS 350 do an equal job of transmitting their engine's power to their wheels.
Handling
The Lexus GS 350 has a larger turning radius than the Lexus IS 350, making it slightly more difficult to maneuver in and out of tight spots.
Performance
In terms of horsepower, it's basically a tie between the Lexus GS 350 and the Lexus IS 350.
Utility
In terms of seating you'll be able to fit the same number of people in both the Lexus GS 350 and the Lexus IS 350.
You'll be able to fit about the same amount of groceries into the Lexus GS 350 as you will in the Lexus IS 350.
Warranty
The Lexus GS 350 comes with essentially the same basic warranty as the Lexus IS 350.
Compare the 2014 Lexus GS 350 and the 2014 Lexus IS 350. 
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2014 Lexus
|
2014 Lexus
|
| Cash Back Rebate: | Visit Rebate Center | Visit Rebate Center |
| Low APR Loan: | As low as 0.90% | As low as 0.90% |
| Lease Incentive: | As low as 0.60% | As low as 2.04% |
| City MPG: | 19 | 19 |
| Highway MPG: | 26 - 29 | 26 - 28 |
| Engine(s): | V-6 | V-6 |
| Seating Capacity: | 5 - 5 | 5 - 5 |
| Basic Warranty: | 4 years/50,000 miles | 4 years/50,000 miles |
Safety Rating: Front 
Vehicle safety data is provided by IIHS, the Insurance Institute for Highway Safety, an independent, nonprofit, scientific, and educational organization dedicated to reducing deaths and injuries on the nation's highways. |
Good | Good |
| Safety Rating: Side
Vehicle safety data is provided by IIHS, the Insurance Institute for Highway Safety, an independent, nonprofit, scientific, and educational organization dedicated to reducing deaths and injuries on the nation's highways. |
Good | Good |
| Safety Rating: Rear
Vehicle safety data is provided by IIHS, the Insurance Institute for Highway Safety, an independent, nonprofit, scientific, and educational organization dedicated to reducing deaths and injuries on the nation's highways. |
Good | No Data Avail. |
| Invoice*: | $44,361 - $46,456 | $36,841 - $38,923 |
Days on Lot measures the average number of days a model sits on a dealer's lot before it's sold. This is one predictor of a dealer's willingness to negotiate.
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*MSRP and Invoice prices displayed do not include applicable gas taxes or destination charges.
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