Performance
The Mazda MAZDA5 is likely to feel a tad slow because of its high horsepower-to-weight ratio compared to the Nissan.
Handling
The Nissan Quest and the Mazda MAZDA5 have roughly comparable tires.
With its tighter turning circle, the Mazda MAZDA5 is very likely more agile than the Nissan Quest, something to consider if you do a lot of city driving; on the flip side, note that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The Mazda's engine is markedly smaller than the Nissan's. Remember that smaller engines can be stressed more; however, smaller engines typically get better gas mileage.
The Mazda could learn a lesson or two from the Nissan Quest in terms of pickup.
The Nissan Quest packs quite a wallop compared to the Mazda MAZDA5 when it comes to torque, which is the force that lets you accelerate quickly.
Utility
The Nissan Quest is a better choice than the MAZDA5 as far as hauling capacity, especially if you often need to carry a lot of luggage or animals.
The Nissan Quest will definitely prove more convenient than the Mazda MAZDA5 for those of you with frequent child-cargo.
Convenience
The Mazda MAZDA5's fuel tank will need to be replenished more often than the unit in the Nissan Quest.
Comfort
Taller drivers will quite a bit enjoy the extra head room in the Nissan Quest's front cabin compared to the Mazda MAZDA5.
The Nissan provides more head- and leg-room to your passengers than the Mazda MAZDA5 does.
Dimensions
The Mazda MAZDA5 is likely to feel a tad sluggish because of its high horsepower-to-weight ratio compared to the Quest.
Your wallet will hurt more every time you fill up the Nissan Quest than the Mazda MAZDA5 because of its more capacious tank.
The Mazda MAZDA5 and the Quest compete for the same parking spaces.
The Mazda MAZDA5's shorter wheelbase will likely give a sprier feel in daily traffic. On the flip side, the Quest is likely to have a smoother, more stable ride.
Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. It costs approximately the same to get the Mazda MAZDA5 to the dealership as the Nissan Quest.
The Nissan Quest will tax your gasoline budget quite a bit more than the Mazda will.
The Nissan Quest doesn't pale in comparison to the Mazda MAZDA5 regarding gas mileage.
In terms of MSRP, the Nissan Quest costs significantly more than the Mazda MAZDA5.
Overview
The Nissan Quest and the Mazda MAZDA5 have the same basic after-sale protection.