Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. It costs about the same to get the Lexus GS 450h to the dealership as the DTS.
The Cadillac DTS guzzles a lot of gas compared to the Lexus GS 450h.
In terms of gas mileage, the Lexus and the Cadillac DTS don't differ much.
Regarding MSRP, the Lexus costs roughly as much as the DTS (though the DTS is a tad cheaper).
Utility
Drivers with frequent child-duty might favor the DTS over the Lexus GS 450h.
Convenience
The Cadillac DTS's fuel tank will need to be replenished more often than the unit in the GS 450h.
Comfort
Taller drivers will substantially enjoy the extra head room in the Cadillac DTS's front cabin compared to the Lexus GS 450h.
The ampler interior dimensions of the Cadillac DTS make it roomier for your passengers than the GS 450h.
Dimensions
The Lexus GS 450h's tank is roughly the same size as the Cadillac DTS's, though the Cadillac DTS's is somewhat larger.
The Lexus GS 450h and the DTS compete for the same parking spaces.
Handling
With its tighter turning circle, the Lexus is quite certainly more agile than the Cadillac DTS, something to consider if you do a lot of city driving; on the flip side, note that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The Lexus GS 450h's engine is considerably smaller than the DTS's. Note that a smaller engine usually has to work a little harder; however, smaller engines typically get better gas mileage.
Torque is roughly equivalent to acceleration, and in this respect, the Cadillac DTS isn't much more powerful than the Lexus GS 450h.
Warranty
The Lexus GS 450h and the DTS have the same basic after-sale protection.