Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. The Chrysler 300C is considerably cheaper to get to the dealership than the Lexus ES 350.
The 300C pales in comparison to the ES 350 in terms of gas mileage.
Producing an exact fuel economy evaluation is so hard that some think not even the federal government can do it, but it looks as though the Lexus ES 350 is the winner as far as gas mileage.
The 300C is substantially costlier than the Lexus with respect to MSRP.
Utility
The Chrysler and the Lexus can accommodate the same number of passengers.
Convenience
You will quite certainly have to visit your friendly gas station more often with the Chrysler 300C than with the Lexus ES 350.
Comfort
Taller drivers will significantly enjoy the extra head room in the 300C's front cabin compared to the Lexus ES 350.
The ampler interior dimensions of the Chrysler 300C make it considerably roomier for your passengers than the ES 350.
Dimensions
The Chrysler 300C is substantially more bulky than the Lexus ES 350.
The Lexus ES 350's tank is about the same size as the 300C's, though the 300C's is a bit bigger.
The Lexus ES 350 and the 300C compete for the same parking spaces.
The Lexus ES 350's shorter wheelbase may produce a less-settled highway ride but a nimbler feel in daily traffic than the 300C.
Performance
In terms of horsepower, the Chrysler 300C packs quite a wallop and will knock the Lexus down a few rungs. On the other hand, remember that high horsepower engines often command higher insurance premiums.
Drivetrain
The Chrysler 300C has a bigger engine than the ES 350. Note that smaller engines typically get better gas mileage, but a smaller engine usually has to work a little harder.
Torque equals pickup, and the Chrysler 300C will have picked up and gone by the time the Lexus finally gets moving.
Warranty
The basic after-sale protection that comes with the 300C isn't quite as generous as the Lexus ES 350's.