Utility
The Buick Lucerne will definitely prove friendlier than the Lexus ES 350 for those of you with frequent kid-cargo.
Dimensions
The Buick Lucerne's tank is almost the same size as the Lexus ES 350's, though the Lexus ES 350's is a bit bigger.
The Lexus ES 350 and the Buick Lucerne compete for the same parking spaces.
Convenience
The Buick Lucerne's fuel tank will need to be replenished a bit more often than the unit in the ES 350.
Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. The Buick Lucerne is considerably cheaper to get to the dealership than the Lexus ES 350.
The Buick won't tax your gas budget considerably more than the ES 350 will.
Producing a precise gas mileage evaluation is so tricky that some think not even the federal government can do it, but it looks as though both the Lexus ES 350 and the Lexus ES 350 perform about comparably with respect to fuel economy.
The Lexus isn't much less costly than the Lucerne as far as MSRP.
Handling
With its tighter turning circle, the Lexus ES 350 is quite certainly sprier than the Buick Lucerne, something to consider if you do a lot of city driving; on the other hand, keep in mind that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The Lexus's engine is a little smaller than the Buick Lucerne's, but not terribly so.
Comfort
Taller drivers will significantly enjoy the extra head room in the Buick Lucerne's front cabin compared to the ES 350.
The Buick Lucerne offers more head- and leg-room to your passengers than the Lexus does.
Warranty
The Lexus ES 350 and the Lucerne have the same basic after-sale protection.