Handling
With its tighter turning radius, the Ford Explorer Sport Trac is quite certainly sprier than the Ford F-350, something to consider if you do a lot of city driving; on the other hand, note that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The Ford Explorer Sport Trac's engine is substantially smaller than the Ford F-350's. Remember that smaller engines can be stressed more; on the flip side, smaller engines are often cheaper to fix.
The Ford Explorer Sport Trac could learn a lesson or two from the Ford F-350 in terms of torque.
The Ford F-350 packs quite a punch compared to the Explorer Sport Trac as far as torque, which is the force that lets you accelerate quickly.
Utility
The Ford F-350 is likely a better choice than the Ford Explorer Sport Trac as far as hauling capacity, especially if you frequently need to carry a lot of luggage or big pets.
Drivers with frequent child-duty might favor the F-350 over the Ford Explorer Sport Trac.
The F-350 outpulls the Explorer Sport Trac by a sizeable margin.
Comfort
Taller drivers will substantially enjoy the extra head room in the F-350's front cabin compared to the Ford Explorer Sport Trac.
The ampler interior dimensions of the Ford Explorer Sport Trac make it more spacious for your passengers than the F-350.
Dimensions
The Ford F-350 is significantly heavier than the Ford Explorer Sport Trac.
Your wallet will hurt more every time you fill up the F-350 than the Ford Explorer Sport Trac because of its bigger tank.
The Ford Explorer Sport Trac and the Ford F-350 compete for the same parking spaces.
Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. The Explorer Sport Trac is considerably cheaper to get to the dealership than the Ford F-350.
The Ford Explorer Sport Trac isn't much less expensive than the Ford F-350 in terms of MSRP.
Warranty
The Ford F-350 and the Ford Explorer Sport Trac have the same basic warranty.