Performance
With that kind of horsepower, the Ford E-350 Super Duty is a legitimate sports car.
When it comes to horsepower, the Ford E-350 Super Duty packs quite a wallop and will knock the Dodge Sprinter Van 3500 down a few rungs. On the other hand, bear in mind that high horsepower engines often command higher insurance premiums.
Handling
With their similar turning circles, the Dodge and the Ford E-350 Super Duty likely handle almost the same into and out of tight spots.
Drivetrain
The Ford E-350 Super Duty has a more sizeable engine than the Sprinter Van 3500. Bear in mind that smaller engines are often cheaper to fix, but smaller engines can be stressed more.
Torque is the force that lets you accelerate quickly, and in this respect, the Ford E-350 Super Duty is substantially more powerful than the Dodge.
Utility
Drivers with frequent child-duty might favor the Dodge Sprinter Van 3500 over the Ford E-350 Super Duty.
There's no clear winner between the Dodge Sprinter Van 3500 and the Ford E-350 Super Duty as far as hauling capacity.
Towing is significantly more the Ford E-350 Super Duty's forte than it is the Dodge's.
Dimensions
Your wallet will hurt more every time you fill up the E-350 Super Duty than the Dodge Sprinter Van 3500 because of its bigger tank.
The Ford E-350 Super Duty and the Dodge compete for the same parking spaces.
Cost
The Dodge is significantly costlier than the E-350 Super Duty with respect to MSRP.
Warranty
The Ford E-350 Super Duty and the Dodge Sprinter Van 3500 have the same basic after-sale protection.