Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. The Honda Odyssey is considerably cheaper to get to the dealership than the Dodge Sprinter Van 2500.
Regarding MSRP, the Dodge costs considerably more than the Odyssey.
Utility
The Honda Odyssey will most definitely prove handier than the Dodge for those of you with frequent child-cargo.
The Dodge Sprinter Van 2500 is a better choice than the Honda Odyssey regarding hauling capacity, especially if you frequently need to carry a lot of suitcases or big animals.
Towing is substantially more the Dodge Sprinter Van 2500's forte than it is the Honda Odyssey's.
Dimensions
Your wallet will hurt more every time you fill up the Dodge Sprinter Van 2500 than the Honda Odyssey because of its larger tank.
The Honda fits in smaller parking spaces than the Dodge Sprinter Van 2500.
The Dodge Sprinter Van 2500's longer wheelbase will result in a smoother, more stable ride; on the flip side, the Odyssey may give a nimbler feel in daily traffic.
Performance
In terms of horsepower, the Honda packs quite a wallop and will knock the Dodge Sprinter Van 2500 down a few rungs. However, remember that high horsepower engines often command higher insurance premiums.
Handling
With its tighter turning radius, the Honda Odyssey is definitely more maneuverable than the Dodge Sprinter Van 2500, something to consider if you do a lot of city driving; on the flip side, note that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The Honda Odyssey has a more massive engine than the Sprinter Van 2500. Keep in mind that smaller engines typically get better gas mileage, but a smaller engine usually has to work a little harder.
Torque is roughly equivalent to acceleration, and in this respect, the Dodge Sprinter Van 2500 is significantly more powerful than the Honda Odyssey.
Warranty
The Sprinter Van 2500 and the Honda Odyssey have the same basic warranty.