Utility
Drivers with frequent child-duty might favor the Dodge Sprinter Van 2500 over the Ford E-250.
There's no clear winner between the Ford E-250 and the Dodge Sprinter Van 2500 with respect to hauling capacity.
Towing is substantially more the Ford E-250's forte than it is the Dodge Sprinter Van 2500's.
Performance
Regarding horsepower, the E-250 packs quite a wallop and will knock the Dodge Sprinter Van 2500 down a few rungs. On the other hand, bear in mind that high horsepower engines often command higher insurance premiums.
Dimensions
The Ford E-250 is substantially heavier than the Dodge.
Your wallet will hurt more every time you fill up the Ford E-250 than the Dodge Sprinter Van 2500 because of its larger tank.
The Ford and the Sprinter Van 2500 compete for the same parking spaces.
Cost
In terms of MSRP, the Dodge Sprinter Van 2500 costs tremendously more than the Ford E-250.
Handling
With their similar turning radii, the Dodge and the E-250 likely handle about the same into and out of tight spots.
Drivetrain
The Ford E-250's engine is tremendously larger than the Dodge Sprinter Van 2500's. Remember that bigger engines may use more gas than smaller ones.
Warranty
The Dodge Sprinter Van 2500 and the Ford have the same basic after-sale protection.