Utility
The Ford's larger trunk will accommodate more large things than the Dodge Ram 1500.
Neither the Dodge Ram 1500 nor the Ford F-250 has a marked advantage in terms of seating capacity.
The Ford F-250 is a better choice than the Dodge Ram 1500 in terms of transporting cargo, especially if you often need to carry a lot of cargo or large animals.
The Ford F-250 outpulls the Dodge Ram 1500 by a big margin.
Dimensions
The Ford F-250 is considerably heavier than the Dodge Ram 1500.
Your wallet will hurt more every time you fill up the F-250 than the Ram 1500 because of its bigger tank.
The Dodge Ram 1500 and the Ford F-250 compete for the same parking spaces.
The Dodge Ram 1500's shorter wheelbase will likely give a more maneuverable feel in daily traffic. However, the Ford is likely to have a smoother, more stable ride.
Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. It costs about the same to get the Dodge Ram 1500 to the dealership as the Ford F-250.
The Ram 1500 is substantially less expensive than the Ford F-250 in terms of MSRP.
Handling
With its tighter turning circle, the Dodge Ram 1500 is most certainly more agile than the Ford F-250, something to consider if you do a lot of city driving; on the flip side, bear in mind that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The Ford has a bigger engine than the Ram 1500. Bear in mind that smaller engines are often cheaper to fix, but a smaller engine usually has to work a little harder.
The Ford F-250 packs quite a punch compared to the Dodge Ram 1500 as far as torque, which is the force that lets you accelerate quickly.
Torque is roughly equivalent to acceleration, and in this respect, the F-250 is tremendously more powerful than the Dodge Ram 1500.
Comfort
While the front cabin in the Ford F-250 offers a bit more head room than the Dodge Ram 1500, there honestly isn't much of a difference.
The Dodge offers more head- and leg-room to your passengers than the Ford F-250 does.
Warranty
The Ford F-250 and the Dodge Ram 1500 have the same basic after-sale protection.