Utility
The Ford F-350 is a better choice than the Silverado 1500 as far as transporting cargo, especially if you often need to carry a lot of cargo or massive animals.
The Ford F-350 and the Silverado 1500 can accommodate the same number of passengers.
The Ford F-350 outpulls the Silverado 1500 by a big margin.
Performance
With that kind of horsepower, both the Ford and the Silverado 1500 are genuine speedsters.
Dimensions
The Ford is significantly heavier than the Chevrolet.
Your wallet will hurt more every time you fill up the Ford F-350 than the Chevrolet Silverado 1500 because of its larger tank.
The Silverado 1500 and the F-350 compete for the same parking spaces.
The Silverado 1500's shorter wheelbase may produce a less-settled highway ride but a sprier feel in daily traffic than the Ford F-350.
Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. It costs about the same to get the Ford F-350 to the dealership as the Chevrolet Silverado 1500.
The Chevrolet Silverado 1500 is substantially less pricey than the Ford F-350 in terms of MSRP.
Handling
With its tighter turning circle, the Silverado 1500 is definitely sprier than the Ford F-350, something to consider if you do a lot of city driving; on the other hand, keep in mind that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The Chevrolet Silverado 1500's engine is a bit smaller than the Ford F-350's, but not terribly so.
The Silverado 1500 could learn a lesson or two from the Ford as far as pickup.
Torque equals pickup, and the Ford F-350 will have picked up and gone by the time the Chevrolet Silverado 1500 finally gets moving.
Comfort
While the front cabin in the Chevrolet Silverado 1500 offers a bit more head room than the Ford, there frankly isn't much of a difference.
The Chevrolet Silverado 1500 provides more head- and leg-room to your passengers than the Ford does.
Overview
The Chevrolet Silverado 1500 and the F-350 have the same basic warranty.