Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. It costs roughly the same to get the Ford F-250 to the dealership as the Chevrolet Silverado 1500.
The Ford F-250 is substantially costlier than the Silverado 1500 when it comes to MSRP.
Utility
The Ford's larger trunk will accommodate more large objects than the Chevrolet Silverado 1500.
Neither the Silverado 1500 nor the Ford F-250 has a marked advantage when it comes to seating capacity.
The Ford F-250 is a better choice than the Chevrolet Silverado 1500 in terms of hauling capacity, especially if you frequently need to carry a lot of cargo or sizeable pets.
The Ford F-250 outpulls the Chevrolet Silverado 1500 by a sizeable margin.
Comfort
While the front cabin in the Chevrolet Silverado 1500 offers a bit more head room than the Ford F-250, there frankly isn't much of a difference.
The Silverado 1500 offers more head- and leg-room to your passengers than the Ford F-250 does.
Dimensions
The F-250 is substantially more bulky than the Chevrolet Silverado 1500.
Your wallet will hurt more every time you fill up the F-250 than the Chevrolet Silverado 1500 because of its larger tank.
The Chevrolet Silverado 1500 and the Ford F-250 compete for the same parking spaces.
The Silverado 1500's shorter wheelbase will likely give a more agile feel in daily traffic. On the other hand, the Ford F-250 is likely to have a smoother, more stable ride.
Handling
With its tighter turning circle, the Silverado 1500 is definitely more maneuverable than the Ford F-250, something to consider if you do a lot of city driving; on the other hand, keep in mind that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The Ford F-250's engine isn't much more sizeable than the Chevrolet's.
Torque is roughly equivalent to acceleration, and in this respect, the Ford F-250 isn't much more powerful than the Chevrolet Silverado 1500.
Warranty
The Ford and the Chevrolet Silverado 1500 have the same basic warranty.