Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. The Colorado is significantly cheaper to get to the dealership than the Sierra 2500HD.
The Chevrolet Colorado is tremendously less pricey than the GMC Sierra 2500HD in terms of MSRP.
Utility
The GMC's larger trunk will accommodate more big items than the Chevrolet Colorado.
The Sierra 2500HD will most certainly prove more practical than the Chevrolet Colorado for those of you with frequent kid-cargo.
The GMC Sierra 2500HD is likely a better choice than the Chevrolet as far as transporting cargo, especially if you frequently need to carry a lot of stuff or large dogs.
The Sierra 2500HD outpulls the Chevrolet Colorado by a sizeable margin.
Comfort
Taller drivers will significantly enjoy the extra head room in the GMC Sierra 2500HD's front cabin compared to the Chevrolet.
The GMC Sierra 2500HD provides more head- and leg-room to your passengers than the Chevrolet Colorado does.
Dimensions
The GMC is tremendously more bulky than the Chevrolet.
Your wallet will hurt more every time you fill up the GMC Sierra 2500HD than the Colorado because of its larger tank.
The Chevrolet fits in smaller parking spaces than the GMC Sierra 2500HD.
The Chevrolet's shorter wheelbase will likely give a more maneuverable feel in daily traffic. On the flip side, the GMC Sierra 2500HD is likely to have a smoother, more stable ride.
Performance
With that kind of horsepower, both the Chevrolet and the GMC Sierra 2500HD are legitimate speedsters.
Handling
With its tighter turning circle, the Chevrolet Colorado is quite certainly more agile than the GMC Sierra 2500HD, something to consider if you do a lot of city driving; on the other hand, note that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The GMC Sierra 2500HD's engine is tremendously more sizeable than the Chevrolet Colorado's. Bear in mind that bigger engines may use more gasoline than smaller ones.
The Chevrolet could learn a lesson or two from the GMC Sierra 2500HD as far as torque.
The GMC Sierra 2500HD packs quite a wallop compared to the Chevrolet when it comes to torque, which is roughly equivalent to acceleration.
Warranty
The GMC Sierra 2500HD and the Chevrolet Colorado have the same basic warranty.