Performance
With that kind of horsepower, both the Chevrolet Colorado and the Silverado 2500HD are legitimate speedsters.
Handling
With its tighter turning radius, the Chevrolet Colorado is definitely more maneuverable than the Chevrolet Silverado 2500HD, something to consider if you do a lot of city driving; on the flip side, keep in mind that a vehicle with a tight turning circle may feel a bit twitchy on the highway.
Drivetrain
The Chevrolet Silverado 2500HD's engine is tremendously bigger than the Colorado's. Note that more massive engines may use more gasoline than smaller ones.
Torque equals pickup, and the Chevrolet Silverado 2500HD will have picked up and gone by the time the Chevrolet Colorado finally gets moving.
Torque is roughly equivalent to acceleration, and in this respect, the Silverado 2500HD is tremendously more powerful than the Chevrolet Colorado.
Utility
The Chevrolet Silverado 2500HD's bigger trunk will accommodate more large objects than the Chevrolet Colorado.
The Chevrolet Silverado 2500HD will quite certainly prove more practical than the Colorado for those of you with frequent child-cargo.
The Chevrolet Silverado 2500HD is likely a better choice than the Chevrolet Colorado when it comes to transporting cargo, especially if you frequently need to carry a lot of luggage or dogs.
Towing is considerably more the Chevrolet Silverado 2500HD's forte than it is the Chevrolet Colorado's.
Comfort
Taller drivers will significantly enjoy the extra head room in the Silverado 2500HD's front cabin compared to the Chevrolet Colorado.
The Chevrolet Silverado 2500HD provides more head- and leg-room to your passengers than the Chevrolet Colorado does.
Dimensions
The Chevrolet Silverado 2500HD is tremendously heavier than the Chevrolet Colorado.
Your wallet will hurt more every time you fill up the Chevrolet Silverado 2500HD than the Chevrolet Colorado because of its bigger tank.
The Chevrolet Colorado fits in smaller parking spaces than the Chevrolet Silverado 2500HD.
The Chevrolet Colorado's shorter wheelbase will give a more maneuverable feel in daily traffic. However, the Chevrolet Silverado 2500HD is likely to have a smoother, more stable ride.
Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. The Chevrolet Colorado is significantly cheaper to get to the dealership than the Silverado 2500HD.
When it comes to MSRP, the Chevrolet Silverado 2500HD costs tremendously more than the Chevrolet Colorado.
Warranty
The Chevrolet Silverado 2500HD and the Chevrolet Colorado have the same basic after-sale protection.