Utility
The RX 400h is likely a better choice than the Cadillac SRX in terms of transporting cargo, especially if you frequently need to carry a lot of suitcases or massive beasts.
Drivers with frequent kid-duty might favor the Cadillac SRX over the RX 400h.
The Lexus RX 400h outpulls the Cadillac SRX by a large margin.
Performance
With its very low horsepower-to-weight ratio, the Cadillac SRX will knock you back into your seat when you step on the gas.
Dimensions
The Lexus is quite a bit more ponderous than the SRX.
Your wallet will hurt more every time you fill up the Cadillac SRX than the Lexus RX 400h because of its more capacious tank.
The Cadillac SRX rides lower than the Lexus, which is a good thing for its center of gravity and ease of access.
The Lexus RX 400h and the Cadillac SRX compete for the same parking spaces.
The RX 400h's shorter wheelbase will give a sprier feel in daily traffic. However, the Cadillac SRX is likely to have a smoother, more stable ride.
Convenience
You'll quite certainly have to take the Cadillac SRX for a fill-up more often than the RX 400h because of its tank size and gas mileage.
Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. It costs about the same to get the RX 400h to the dealership as the Cadillac SRX.
In terms of gas mileage, the Lexus RX 400h bests the Cadillac.
The Lexus RX 400h isn't much more expensive than the Cadillac SRX as far as MSRP.
The Lexus will save you a bundle at the pump every year compared to the SRX.
Handling
The Cadillac's rear-wheel drive layout likely gives it better dry traction than the Lexus RX 400h; however, the Lexus RX 400h's front-wheel drive layout likely provides better traction in rain, snow or ice.
The Cadillac SRX and the Lexus have about comparable tires.
With their comparable turning radii, the Lexus RX 400h and the SRX definitely handle approximately the same into and out of tight spots.
Drivetrain
The Cadillac SRX's engine is markedly more massive than the Lexus RX 400h's. Remember that more massive engines may use more gas than smaller ones.
Torque equals pickup, and the Cadillac SRX will have picked up and gone by the time the Lexus RX 400h finally gets moving.
Torque is the force that lets you accelerate quickly, and in this respect, the Cadillac SRX is quite a bit more powerful than the Lexus RX 400h.
Overview
The RX 400h and the Cadillac SRX have the same basic warranty.