Utility
The Enclave will most certainly prove friendlier than the Ford for those of you with frequent kid-cargo.
Dimensions
Your wallet will hurt more every time you fill up the Buick Enclave than the Ford Flex because of its bigger tank.
The Enclave and the Ford Flex compete for the same parking spaces.
Convenience
You will most certainly have to visit your friendly gas station more often with the Ford Flex than with the Buick.
Cost
As far as MSRP, the Enclave costs considerably more than the Ford Flex.
Handling
With their similar turning radii, the Enclave and the Ford Flex quite certainly handle approximately the same into and out of tight spots.
Drivetrain
The Ford Flex and the Buick have similar-sized engines, with a slight advantage to the Buick.
The Ford Flex has no lessons to learn in terms of torque from the Buick Enclave.
Torque is roughly equivalent to acceleration, and in this respect, the Buick Enclave isn't much more powerful than the Ford Flex.
Comfort
Taller drivers will significantly enjoy the extra head room in the Ford Flex's front cabin compared to the Buick.
The Flex offers more head- and leg-room to your passengers than the Buick Enclave does.
Warranty
The basic warranty that comes with the Ford isn't quite as generous as the Buick Enclave's.