Cost
The destination charge is a standard charge for transporting the vehicle from its point of origin to the dealer. It costs almost the same to get the Honda Odyssey to the dealership as the Toyota Sienna.
The Toyota Sienna won't tax your gas budget significantly more than the Honda Odyssey will.
The Honda Odyssey is considerably more expensive than the Toyota Sienna as far as MSRP.
Utility
The Odyssey will most certainly prove more practical than the Sienna for those of you with frequent kid-cargo.
There's no clear winner between the Toyota Sienna and the Honda with respect to transporting cargo.
Convenience
You definitely won't have to visit your friendly gas station more often with the Toyota Sienna than with the Odyssey, as both offer comparable mileage ranges.
Comfort
Taller drivers will considerably enjoy the extra head room in the Toyota's front cabin compared to the Honda Odyssey.
The Honda Odyssey is not particularly more spacious for your passengers than the Toyota.
Dimensions
The Toyota Sienna's tank is about the same size as the Honda Odyssey's, though the Honda Odyssey's is slightly bigger.
The Toyota Sienna and the Honda Odyssey compete for the same parking spaces.
Handling
With their comparable turning circles, the Honda and the Toyota Sienna quite certainly handle about the same into and out of tight spots.
Drivetrain
The Toyota Sienna's engine isn't much more sizeable than the Honda Odyssey's.
Overview
The Honda and the Toyota Sienna have the same basic warranty.